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B12 Folic Acid

Vitiligo is a chronic skin condition in which the color/pigment making cells (melanocytes) in the skin are destroyed or not functioning properly and as a result smooth, white, depigmented patches appear on one’s skin. Almost 1-2% of the world’s population is affected by this disease. Although, Vitiligo has been discovered way back in time, the exact cause of it and the perfect treatment for it still under research. One of the many recent studies showed that the intake of B12 vitamin and Folic Acid, along with sun exposure could be helpful in treating Vitiligo.

The research was conducted by the Department of Dermatology, University Hospital, Uppsala, in Sweden to test the hypothesis whether B12 Folic Acid and sun exposure could prove to be helpful in curing Vitiligo. One hundred patients with Vitiligo were treated with oral folic acid and vitamin B12 after being informed that sun exposure might enhance repigmentation. They were requested to keep a record of sun exposure in summer and UVB irradiation in winter. The minimal treatment time suggested was 3-6 months but should be longer if improvement was achieved. Clear repigmentation occurred in 52 patients, including 37 who exposed their skin to summer sun and 6 who used UVB lamps in winter. Repigmentation was most evident on sun-exposed areas, where 38% of the patients had previously noted repigmentation during summer months. Total repigmentation was seen in 6 patients. The spread of vitiligo stopped in 64% of the patients after treatment. Folic acid and vitamin B12 supplementation combined with sun exposure can induce repigmentation better than either the vitamins or sun exposure alone. Treatment should continue as long as the white areas continue to repigment.

However, further studies are required to determine the ideal minimal dosages of vitamins and UV exposure, as well as the duration of treatment.

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